An EUS-FNB needle (EUS-guided fine needle biopsy needle) takes a tissue core for histology from pancreatic masses and submucosal lesions under endoscopic ultrasound (EUS) guidance. SonoTip TopGain is a single-use EUS core biopsy needle with a three-point crown cut tip (Franseen type), on a stainless steel shaft, in 19G, 22G and 25G.
This page is intended for healthcare professionals.
Schematic, not to scale
| Needle (G) | Needle diameter (mm) | Sheath outer diameter (mm) | SUT code | Model |
|---|---|---|---|---|
| 19 | 1.1 | 2.1 | GS1810 | GUB-33-21-019 |
| 22 | 0.7 | 1.8 | GS1810 | GUB-33-18-022 |
| 25 | 0.5 | 1.8 | GS1820 | GUB-33-18-025 |
An endoscopic ultrasound fine needle biopsy (FNB) system with a crown-cut needle tip for core-tissue sampling.
EUS-FNB (EUS-guided fine needle biopsy) is a biopsy taken with a needle passed through the working channel of the echoendoscope under endoscopic ultrasound (EUS) guidance. It aims for a tissue core with preserved architecture, for histology and immunohistochemistry. The EUS-FNB needle is single use. Acquire from Boston Scientific, EchoTip ProCore from Cook Medical and SonoTip TopGain from Medi-Globe are EUS-FNB needles of the same product class; the list is not complete and implies no ranking or superiority. Melekırmak is the Medi-Globe distributor in Türkiye, and this page describes SonoTip TopGain, a stainless steel needle with a three-point crown cut tip.
In short: FNA brings back cells for cytology, and FNB aims for a tissue core for histology. An FNA needle has a bevelled cutting tip and brings back cells and cell clusters, so the diagnosis is mostly cytological. An FNB needle aims for a tissue core with preserved architecture, for histology and immunohistochemistry. For solid pancreatic masses the ESGE 2025 guideline prefers end-cutting FNB needles over reverse-bevel FNB and FNA (strong recommendation, high quality evidence); where on-site cytology (ROSE) is available, FNA keeps a role. ASGE 2024 also prefers FNB over FNA (strong recommendation) and 22G over 25G (conditional recommendation). The guidelines name needle types, not products, and the choice of needle is the physician's decision. The FNA needle of this range is on the ProControl page.
A crown cut tip has three points and is designed to take a tissue core. In a randomised study (Kovacevic et al., Endosc Ultrasound 2023, n=64) the median number of tissue microcores per pass was 3 with the FNB needle and 2 with the FNA needle, and the mean total tissue area was 2.74 mm2 against 0.44 mm2, about six times (P<0.001 for both). The FNB needle in the study was the modified Franseen type TopGain.
The models table pairs them: the 19G needle is 1.1 mm on a 2.1 mm sheath, and the 22G and the 25G needle are 0.7 and 0.5 mm on a 1.8 mm sheath. The sheath diameter is what has to pass the working channel of the echoendoscope, so it is the number to check before the case.
On the handle. The needle length adjustment is 0 to 8.5 cm, set and locked on the Twist-Lock ring with one hand, and the same ring sets the sheath length.
The price depends on the model (19G, 22G or 25G) and the quantity. We do not publish a list price on this page. Use the quote button on this page for a fast quote. We quote for hospitals in Türkiye and answer international enquiries.
Yes. Melekırmak, based in Istanbul, is the Medi-Globe distributor in Türkiye and supplies hospitals nationwide. SonoTip TopGain EUS-FNB is ordered as GUB-33-21-019 (19G), GUB-33-18-022 (22G) or GUB-33-18-025 (25G). The nitinol TopGain Flex is coming soon and cannot yet be ordered. International enquiries are answered as well: availability, documentation and lead times depend on the country, so send the order number, the quantity and the destination country with your request.
Based in Istanbul, Türkiye, we supply hospitals nationwide and answer international enquiries. Ask us about availability, documentation and lead times in your country.
Updated: 09.11.2026
