An EBUS-TBNB needle (endobronchial ultrasound-guided transbronchial needle biopsy) is designed to take a tissue core from mediastinal and hilar lymph nodes or intrapulmonary lesions under ultrasound. It is used when the tumour board needs tissue architecture or molecular testing. SonoTip TopGain is a single-use 22G needle with a three-point crown cut tip, on a stainless steel or nitinol shaft.
This page is intended for healthcare professionals.
Schematic, not to scale
| Shaft | Bronchoscope | SUT code | Model |
|---|---|---|---|
| Stainless steel | Olympus BF-UC190F and BF-UC180F, Fujifilm | GHC1790 | GUB-45-18-022 |
| Nitinol | Olympus BF-UC190F and BF-UC180F, Fujifilm | No code | GUB-46-18-022 |
| Nitinol | Pentax | No code | GUB-42-18-022 |
The two Olympus and Fujifilm builds come with a separately packed Fujifilm adapter.
An EBUS core biopsy needle with a crown-cut tip: an EBUS transbronchial needle biopsy (TBNB) system for core-tissue sampling of mediastinal, hilar and intrapulmonary lesions.
EBUS TBNA (transbronchial needle aspiration) aspirates cells through a fine needle, and the aspirate goes to cytology. EBUS TBNB (transbronchial needle biopsy) uses a crown cut needle, a tip with three points, designed to take a tissue core, so the sample can be read as tissue. Both are done with an EBUS bronchoscope under ultrasound.
Three order numbers, all 22G at 0.7 mm with a needle length adjustment of 0 to 4 cm and a 1.8 mm sheath outer diameter: one on a stainless steel shaft and one on a nitinol shaft for Olympus and Fujifilm, and one on a nitinol shaft for Pentax.
A 2026 meta-analysis (Li et al., Eur Respir Rev, 11 studies, 1,434 patients) found a diagnostic yield of 88.5% with TBNB and 80.1% with TBNA. The odds ratio was 5.22 in lymphoma and 2.88 in sarcoidosis, with no difference in lung cancer (OR 1.18). The authors stress that randomised evidence is limited and most studies are observational. The choice of needle is the physician's decision.
PD-L1 suitability did not differ between 22G TBNB and 22G TBNA in a multicentre randomised trial of 154 patients (Kramer et al., Lung Cancer 2023): 80.0% and 76.7%, p=0.633. Tissue cores were more frequent in TBNB samples (72.0% and 41.0%). The ERS/ESGE/ESTS 2026 guideline also reports a high rate of PD-L1 suitability in EBUS-TBNA samples.
The price depends on the order number (shaft material and scope build), the quantity and the delivery terms. We do not publish a list price on this page. Write to us and we will prepare a quote. We quote for hospitals in Türkiye and answer international enquiries.
Yes. Melekırmak, based in Istanbul, is the Medi-Globe distributor in Türkiye and supplies hospitals nationwide. SonoTip TopGain EBUS TBNB is ordered as GUB-45-18-022 (stainless steel) or GUB-46-18-022 (nitinol) for Olympus and Fujifilm, and as GUB-42-18-022 (nitinol) for Pentax. International enquiries are answered as well: availability, documentation and lead times depend on the country, so send the order number, the quantity and the destination country with your request.
Based in Istanbul, Türkiye, we supply hospitals nationwide and answer international enquiries. Ask us about availability, documentation and lead times in your country.
Updated: 09.11.2026
