Helicobacter pylori Rapid Urease Test

A rapid urease test kit (the kind of test known as CLOtest, or CLO test) shows Helicobacter pylori urease activity in a gastric biopsy specimen taken at gastroscopy. It is an in-vitro test. The colour change is read by eye within minutes at the endoscopy table, so no analyser is needed and the specimen is not transported before the result.

This page is intended for healthcare professionals.

Helicobacter pylori Rapid Urease Test

A rapid in-vitro diagnostic test kit that detects Helicobacter pylori urease activity in gastric biopsy specimens during endoscopy.

In which cases?

  • Dyspepsia, gastritis or peptic ulcer disease worked up at gastroscopy.
  • A biopsy taken to decide on eradication therapy before the patient leaves the unit.
  • A follow-up gastroscopy after eradication therapy, to see whether the reaction has gone.

What makes it different?

  • Reads out within minutes, so eradication can be discussed in the same visit.
  • Colour change read by eye, so no reader or analyser is needed in the room.
  • Uses the biopsy specimen already taken, so there is no extra pass with the forceps.
  • Read at the endoscopy table, so the specimen is not transported before the result is taken.

Frequently asked questions

What is a rapid urease test for H. pylori (CLO test)?

A rapid urease test is an in-vitro test on a gastric biopsy specimen that shows the urease activity of Helicobacter pylori. The colour change is read by eye within minutes. It uses the biopsy specimen already taken at gastroscopy, so there is no extra pass with the forceps.

How does the rapid urease test work, and how long does it take?

The test is done on the biopsy specimen taken at gastroscopy and read at the endoscopy table, and the result is available within minutes. The colour change is read by eye, so eradication can be discussed in the same visit. This page does not give a fixed reading time or sensitivity figures.

What does a positive or a negative rapid urease test (CLO test) mean?

A positive result means that urease activity was seen in the biopsy specimen, and the test shows the urease activity of Helicobacter pylori. Biopsy-based tests lose sensitivity during bleeding, and the ESGE advice on peptic ulcer bleeding on this site is to look for Helicobacter pylori in the acute phase and to repeat the test if the result is negative (Gisbert and Abraira, Am J Gastroenterol 2006;101:848-863). Reading the result and deciding on treatment belong to the physician.

Is a CLO test the same as a rapid urease test?

CLO test is used in everyday language for the whole class of rapid urease tests, and CLOtest is one of the names under which this kind of test is known. This page describes a rapid urease test for gastric biopsy specimens taken at gastroscopy, which belongs to that class. It makes no claim that it is better than another test, and it says nothing about the availability of other products.

Rapid urease test or urea breath test: what is the difference?

The rapid urease test is done on a gastric biopsy specimen, so it is used in a patient who is having a gastroscopy. Breath, stool and blood tests do not need an endoscopy. Which test to use is the physician's decision.

What is in a rapid urease test kit?

This page does not list the kit contents, the pack size, the storage conditions or the shelf life. It says only that the test is read by eye, as a colour change, on a gastric biopsy specimen taken at gastroscopy. To get the kit contents, the pack size, the storage conditions and the shelf life, ask with an export quote: use the Request an export quote button at the bottom of this page.

What is the price of a rapid urease test kit, and how do I get an export quote?

We do not publish a list price on this page. The price depends on the quantity and the delivery terms. To get an export quote, use the Request an export quote button at the bottom of this page and name the quantity and the destination country.

Who supplies rapid urease test kits in Türkiye, and can I ask for an export quote?

Melekırmak, an Istanbul-based medical device distributor, offers this rapid urease test kit for Helicobacter pylori. For availability, documentation and lead time in your country, use the Request an export quote button at the bottom of this page and name the quantity and the destination country. The colour change is read by eye at the endoscopy table, so the unit needs no analyser.

Export and Bulk Orders

Based in Istanbul, Türkiye, we supply hospitals nationwide and answer international enquiries. Ask us about availability, documentation and lead times in your country.

Request an export quote

Updated: 09.11.2026

Distributing Helicobacter pylori Rapid Urease Test in Türkiye

Registration, the first cases and nationwide supply are handled by one team.